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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a569d24d0508bb098cebff0df06c3146910f04e1eea3fbc417a218e05e2559ff' 
  AND token = 'qi+x6jNA8iowLp34waXA38Y9v48iBZ2/5DSesC/Mriw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}