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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '87da9aa34446af0cb868c01e39e8e35205d8a16c2158a84459a08e0dcd95f195' 
  AND token = 'NWME1vtys5fdgQxnMmkzCXmDvbrvRv3hJIPVh8VKnmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}