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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a68177c2048da39f90d9f2859d16239b8b5c376a6975ea8c84fa5b1a598cec78' 
  AND token = 'zQh9y7OrTFcf+Kd46nQGAK2DFUHj1PtrDX3nFD3o+zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}