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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0bd5d28cd231df963e79fef51601d55bf48b935d0a567f6b3b4a81ba02e52658' 
  AND token = '45G37CGOf1axP0XCGy7XHsaKq1I4KLuveNlt55BnFss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}