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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '85112964e11f08843417b84fe7004bffb7bf5553d1aaccabf8e4498f106b284a' 
  AND token = 'MKEmE9/UFpFsELW1kBOWuDPCxh2xAXM+t/LD0HO3ubs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}