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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aec83fbd7411737a49d326eeb922a4b276d5db77bf6cec813bd944be53abec60' 
  AND token = 'fOhKFAaR7aXafcq1rtJas4m05BfvMBDMPS/RfsSOb0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}