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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5a5cc31badee1843f99018c27b1aae63387bb63c3ab9b110bf27d087b7f35bc5' 
  AND token = 'PIOGpA+VgU40mwRf8Dt57s+RAR2lJwc0k+/yV+iaGCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}