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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d100f8ef4df99de2ba790acb42ddffd191dcc2cbbd118532156dff0fe53556d' 
  AND token = 'nxfwO7N92D3jK27ajEEp22tsNd9IBEqTq/rsD4PkEQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}