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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '075ec1aa075bc88f2a15cc0a9b70c19c0f2c43635a890e23b49491336dca6a04' 
  AND token = 'NKX8YhWub84vYolj1uQ4AE5zMuVJVVRHpay0S4b7qRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}