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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea22a8fd2c8f5a35eaa74562a4386dd4357e72913a57971ba02f49d920d99fc5' 
  AND token = 'tnwFUBHaaX00iDjFUFEGTUzyBxvOA2AY8IN9fjTPy+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}