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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0999dc83efe616a090f18844d891cb2a13403aa6732b201a1ac44732dd1460ba' 
  AND token = 'o+TTs7574rk28RD/FHPdwqPyCps0wviNBTVTRkCnZOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}