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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78c28805e52a9adb8cf90f4c6945301b733d3f767cf717a5f9330d69213f5f9c' 
  AND token = 'PVpOhSiGE1JPCrEZ1aihl2oXoALlNf5F+BEE7eJaHEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}