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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5a9af64aeae578a070ab2187843e67a352e90a584f41eeeef1264d587a4e26e6' 
  AND token = 'JQF8saTK/bvtvmAR2efYR1ydhVTcY+u8/fa5WXOzSFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}