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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ce321a7883cff06ba559afa370655146bc88f041f433e41c2e58f09546730d01' 
  AND token = 'JO6z3rGSiTMS3nTLKtEm2EzjOR/i6kX33ab9TPjUynQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}