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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '74cdb59c59c2013dec7cbb760ae3d9b3b556b620da1533e989206e05cf524b7b' 
  AND token = 'cYi8HNy308tDJTcTOmi5+8PHRG5FhsjLQxDBQG+IGr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}