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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '27cfac1a1ef07e2eaa28fad4edefc0d757af7b721f3179e0f061b1098302fec5' 
  AND token = 'LFH2g+8wO/Hf0Offd7Ep9OtBg+aAXchod72kZyfQWUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}