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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22f8af0dab7862dcd79f317c976d5f137993e0a053b9cd2d778f9b26e8f1edca' 
  AND token = 'd/qGFAxqMPvokQFUGMauSA5gNG/LDz1z0tScmRvEKwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}