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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd3f72aaa6cb43c97de5500769b9a18cd6b367b148f98716480c2adf4d2ea66a1' 
  AND token = 'FCVoZ/I7tiOSiliAgSVAXUmf4E1hc+wVEqXRMoe14vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}