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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cee52479601fc87bfed34545316ac008e75df79a10c253f97106260b69b0b755' 
  AND token = 'qoR9AcUTeC385jV786uSeYL0qTwYSAOw2fVxNovBv5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}