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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59194ec60b6cf4f4572c2beffae87e71b82432c49cd01484734b9cd484c65d94' 
  AND token = 'VIrmMIH9lMm45PWKMiEKkmStE3z3vhA84WhUSUdjqOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}