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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a50794ec9baf11898e7b750a75fb99b5f8007f274475dffef1ba2bc5abd2ee70' 
  AND token = 'Q0kv3qNDpQc1i+2KzBD6nd/dcBIMmr7gPltn7nUl3BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}