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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d737d0948b6d6e158968ed49a3f7b073e63835a0acd6eaf041479621b168556' 
  AND token = '9hHDlHPZginrO8kERN6ldYK2xyBh71Ih9YRfnH21DLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}