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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '495cc83c33e0813d379c3146b029a847d1a99afbfc274fae963a333203bbfb9d' 
  AND token = '73NoTB1dRRGo+iSwJFb0Rz0b4RkNuzsTLzKjWe7BRDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}