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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fc6cc2d2da08700e8456510500a880bd0b4589519693d84de86d108192322718' 
  AND token = '69dBf1xn89ORN5S+J2eQuU2cAyYKPtFl54s48aanULY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}