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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05e8584c6ecc35d4a147ce460d9f5b7da726f4e6b82516be2dfc255a9c23c334' 
  AND token = 'EKdnuEwdrTMdW0XRAKWT0K/7jlaST1feL/4sqerobXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}