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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3abe9237708bc7151e2d121302c9f719aed342539ebde98d2705e87895a20b57' 
  AND token = 'BPhEqvrMlaKIQ5MNwB7RzADuPLwl5/WVixFvIF8vMnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}