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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb4d82341b681a9606f664cb5c77977060be09da64aa8ee76dc059875b62eeab' 
  AND token = 'u2Ug5IoTSJrtezxzmEPkEjmdz6ZKBOaGTCXhJimcdls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}