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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a6b868c5c89a1889e72e068f6847ec7a697615d0e5ac75eb58df7c0b26d1065' 
  AND token = 'GyuUmR+F59X9m/9X6IEWrva3pc9ZomqPkZBge8QMIHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}