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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5000386d47ecf91e200164630df86ae2643579528b4b4ef331c2835e147b3c92' 
  AND token = 'yiUZPPQEU2MKf/YhXnv4PEUzOMTZI21egBITlytT6Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}