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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '621b8377059c8d03e550ef538c106b0e164741250c1717263e214aca5673d827' 
  AND token = '0aSpy9qXrnccsjxqCJfKe3mk/byq8UXavBE3LX2HSmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}