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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd80ccb43aae475f47157fa987368dc49dade3a539d47aceff27d2f4a4acdbeb8' 
  AND token = '/kF71/DedWtxLaXV3ardhC6hCvXlv/A2zdz6X3BfGNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}