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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21411d0054ba27ccc4d0010a5ed7baf1eac76ae2809fa895f59f32eb3869b0d1' 
  AND token = 'QoVKyYhaYX8e1zFdPWajHFNPQATDGp0pqSMAHwz8hFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}