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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa75b5d2cb7ee4df5beca42e1b43f2cdf608d5b70b218973008ee5e66a316319' 
  AND token = 'c5UseExNxV3MjP4MpjJwFENSRkiUQ5rsafz0UmTNdvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}