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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5527f71770abf44777e31dcd3b59ac2dd2a2a5f086e94153777d904f2e869490' 
  AND token = 'VnfHrLaTsumB6przY+2F5LkmNLJFPYDIkcSbzjp0irs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}