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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'edffa31651ab659ccac3f74e474ec3bb0ba7b42708072895cb22c73669a0f94b' 
  AND token = 'X3Y25S8f8eeFmVfmnWODee6WwvWoJ/WUPndxgxp8LZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}