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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0cd7a8aace124901af430470dc42c2bdec1e2c95f9154d535f9428283722f130' 
  AND token = 'uM0JUf/06C2wMmSC3WyZMSCfrmFnP2zK0YagEvZnHRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}