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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '96a0887db936855c1e9a37359df093902b882514161a3d7110785e41686fba4c' 
  AND token = '042GnTjno5YqyFiEIdjc/1GNsc064ghoQDzWNqBiqGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}