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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0aff5b80130e2f9f676954307edf966e45247554cfaf2cff42ae4ca59c1cda26' 
  AND token = '22pIA9GIqoxFfaDhhhYWK8SiZ6FUSQdlbbjpd83xbhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}