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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '88ed7c48751a1c9636ea99e2d71a9dfd835096b83f12ef79759047402709d6c6' 
  AND token = 'YJ79CE1E7W6OMLjXAlRr+VU8I0Ciob1TaJOZcTs8DWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}