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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fb245190bba54faa06afacc7039d376321f69d7a09294a4f5afcb5ae225bb82c' 
  AND token = 'Dp8w2Jqmno5BciRJykv7gu32Y8bmrO4dmXQYTy5u8n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}