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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a728804c6580fc42534e8e00c9df83ff2171b82f0898128ff6d8596b43118a4a' 
  AND token = 'ik7TU+2B53s6oKX300G8QhJabwTHH6S9BwFj8FTC/L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}