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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b80654dbf320e499de4095921170d0215f4f305934ca895560e1618851a3f741' 
  AND token = '+pcIMxnorUP8h9f261RmncbuDNuAW7KweRD4LzdH/l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}