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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '00e19647064e003c7fca5ace465191d77cceead41d524abc436524bad56959fe' 
  AND token = '28BHDK20zKc2eknjQWVKgIb2X9PRi/eyRlSUPeyn8Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}