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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6cbfc91b2dc22badab6b40d1c91d57e8d920d92689dc510121b88aeb94da6e2f' 
  AND token = 'G3iahvFQXPGOG3yC/jWKsmFgGapPsutDJE0+U3lQebs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}