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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf544571ccc15871bac4803977190a9b01ed4fcf739e4306b269d51dfed70e3d' 
  AND token = 'a/cZITC8SsV0odhzb9o9ilgxYV5D6qtZmmofUMRU6mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}