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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b583f0ee595854946055e0be3133c8433c7b31bb245e3663633d536749cbd41e' 
  AND token = 'dz351E8Yrv1jpFVBLKVxot61hVbENME1wPvBLWFapN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}