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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f74206172cc20c83a6536d55db340ecc213c1df3698816cb3a153d1487aae52e' 
  AND token = 'k3Z5PtJJtFzTxfQSN1JLk3czPOsTc5DBnMZcp29wjNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}