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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '67a428d5497f8ca3ca57def7195cb04a53f3797b7a968d8ad112c13a518c5918' 
  AND token = 'LwLF5DwCqV6pOp6CLXaPtcPM1nuHd+HqwfcpVm9vPZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}