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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2defcde4568f040a1a99a12205f09be6ca5fc3e87a07c758e5c51eb9c31cae75' 
  AND token = 'r/2qn/d3ZzIKxzD+2T24KIjRIyZGgqb1yiDIuyo5VrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}