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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4fbfdab29787da0318fa94e327999fb0474fad08abc7a50afc1bea24e99e4859' 
  AND token = 'zDiVcCzvD3fw3MeZWv6TENCQx3LbASilW9+BxdquoBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}